In 1965 the Maserati Sebring was revised, and a 4 liter engine was added the following year in the range-topping model. With 265 hp the level of performance was impressive, as attested by the 255 kph top speed (158 mph).

Stylistically, the modifications included a restyled front end with a chrome plate housing the double headlights, a new hood intake and side vents now located higher up on the front wings. The new tail lights were reminiscent of those on the Quattroporte, creating a strong rear-end resemblance. Internally the car was also revised and air conditioning was now available. A combined total of 245 second series Sebring were assembled and in 1969 the last four examples rolled of the assembly line, production having understandably decreased following the launch of the Ghibli two years earlier.

Among the original 593 Sebring owners (including both series) was a young Italian tenor named Luciano Pavarotti and the Austrian crystal glass tycoon Adrian Swarovski.